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Neither manufacturer says, Give it a shot and see what happens. Their official position is that once frozen, the drug should not be used

The gain in apparent affinity through avidity allows us to deliberately tune down the monomeric affinity of individual Fabs, mitigating on-target, off-tissue toxicities

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How much you regain depends on a number of factors: How much weight you lost initially How long you were on treatment What lifestyle changes youve made and maintained People who have genuinely changed their eating habits and activity levels are far more likely to keep the weight off after Wegovy than those who relied solely on the medication