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Recent Advances in Incretin-Based Pharmacotherapies for the Treatment of Obesity and Diabetes

Notably, the gastric emptying effects often diminish over time with continued therapy, which may help reduce some digestive symptoms

23431 (May 1, 2026), the FDA proposed to restrict large-scale 503B compounding of these medications, with a public comment period open through June 29, 2026

These stimulate the gut to produce GLP-1 and other satiety hormones naturally, which may be especially beneficial when discontinuing your medication

Understanding those data flows before you start is part of informed consent

Back Ferguson, D (20 April 2025) 'The end of WeightWatchers