Potential remission: Some patients who lose substantial weight achieve HbA1c below diabetic thresholds, sometimes called remission. While this typically requires ongoing treatment, it represents meaningful disease modification
Most patients start with weekly shots, then move to monthly maintenance once their levels are steady
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Compounded preparations allow dose and frequency customization, potentially reducing needle trauma in sensitive patients
Check with your insurance provider if you're unsure whether your plan provides coverage for B12 shots
In our systematic review and meta-analysis evaluating the clinical efficacy and safety of combinations of DPP-4 inhibitors and SGLT2 inhibitors in patients with inadequately controlled type 2 diabetes, the combination of an SGLT2 inhibitor and a DPP-4 inhibitor showed a greater reduction in HbA1c (weighted mean difference, 0.6%), fasting plasma glucose, and 2-hour postprandial plasma glucose levels than the combination of a placebo with a DPP-4 inhibitor [47]