As discussed above, PKA also phosphorylates perilipin on the lipid droplet, resulting in changes that enhance stimulated lipolysis, including movement of perilipin away from the lipid droplet (21), perilipin-mediated remodeling of lipid droplets that increases the surface area available for lipolytic attack (75), and perilipin-mediated activation of HSL activity at the surface of the lipid droplet (84, 125)
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However, the full benefits of the therapy may take time to manifest and can vary depending on the specific health concerns being addressed