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This gap leaves open the possibility of unintended psychiatric effects, not because the drugs are inherently harmful, but because their impacts haven't been properly studied among users with mental health conditions
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Key Takeaways Standard anastrozole dosing for TRT ranges from 0.25-0.5mg twice weekly Target estradiol levels should remain between 20-40 pg/mL Lab monitoring every 6-8 weeks is essential for proper dosage adjustment Side effects include joint pain, mood changes, and potential bone density loss Not all TRT patients require anastrozole supplementation Standard Anastrozole Dosing Protocols for TRT Most TRT protocols begin anastrozole at 0.25mg every 3.5 days, administered on the same schedule as testosterone injections
doi: 10.1093/jn/nxab309
