For example, the study found GLP-1 users had a 7% greater risk of developing gastroparesis compared with people who were using other types of medications to lower their blood sugar
But the signal is spreading
Similarly, changes in albuminuria appear as the strongest predictor of major kidney outcomes according to the Parameter Response Efficacy (PRE) score, an algorithm integrating several biomarkers of renal adverse events, as treatment with liraglutide resulted in a 16.2% estimated relative risk reduction (RRR) of kidney outcomes, similar to the observed RRR of 15.5%, which was mainly driven by UACR changes (RRR 13.2%) [15]
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Could orforglipron be less expensive than other GLP-1 medications
One study found that 77% of PCOS patients lost more than 5% of their total body weight, and 55% achieved weight loss exceeding 10%