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Nitric oxide - a signaling molecule that causes blood vessels to dilate - is one of the most potent vasodilators in the body

Total RNA was isolated by using TRIzol reagent, treated with DNase I, and converted to cDNA as previously described 66

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The authors also revealed the mechanism: lactate is converted to lactyl-CoA and then transferred to histone lysine residues by a lactyl-transferase