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The no-observed-adverse-effect level (NOAEL) was established at 0.03 mg/kg/week in rats and 0.02 mg/kg/week in monkeys, corresponding to systemic exposures approximately 5- to 8-fold higher than human therapeutic levels
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Protein kinase C activation mediates glucagon-like peptide-1-induced pancreatic -cell proliferation
No Growth Hormone-Related Side Effects Critically, AOD-9604 did not produce any of the adverse effects associated with growth hormone therapy
The pre-operative period is critical to emphasize the importance of vitamin adherence [83,130], and inform the patients about the side effects of vitamin B deficiency
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