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Nature 454:232235 Jagadeeswaran R, Lenny H, Vazquez B et al (2017) The abnormal Presence of mitochondria in circulating red blood cells cause an increased oxygen consumption rate, ROS generation and hemolysis in patients with sickle cell disease

The Annals of pharmacotherapy, 46(2), 240247

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This study concluded that 4 mg twice daily and higher doses might decrease brain atrophy [23]

ONO-3411 and MK-477 have shown anti-inflammatory activity in mouse models, which appears to be exerted through COX inhibition

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