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Note that IGF-1 LR3 is often reconstituted with acetic acid in bacteriostatic water for optimal solubility, unlike most other peptides

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While that gap is meaningful, it was not dramatic enough for AOD-9604 to win approval as a standalone obesity drug, and formal development was paused in 2007

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Several reasons may explain the observation that the mean treatment difference was 12.5% in STEP 1 and 8.7% in SELECT

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