Patients on levothyroxine should have thyroid function monitored after initiating tirzepatide and following dose increases, as adjustments to levothyroxine dosing may be necessary
Specificity of GLP-1R immunostaining in DRG tissue
however, if the symptoms persist, adjustments in dosage or trying out different treatments might be needed
The medication's weight loss mechanism works through GLP-1 receptor activation, not thyroid function, so thyroid absence does not block its primary action
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