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Spike-timing-dependent potentiation of sensory surround in the somatosensory cortex is facilitated by deprivation-mediated disinhibition

Final thoughts Stopping GHK-Cu typically produces gradual benefit decline over 2-4 months without dramatic rebound effects or rapid reversal to pre-treatment baseline, with 30-40% of long-term users (6+ months treatment) maintaining 50-70% of peak improvements indefinitely while shorter-term users show greater regression toward baseline

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52(1):3549 Weidhase R, Kramell H-M, Lehmann J, Liebisch H-W, Lerbs W, Parthier B (1987) Methyl jasmonate-induced changes in the polypeptide pattern of senescing barley leaf segments

Acknowledgements This study was financially supported by grants from the Academy of Finland (AK297267, AK328443, and KK296840, KK333302), the Kuopio University Hospital VTR grant (KK5503743), the Emil Aaltonen Foundation, the Sigrid Juselius Foundation, the Pivikki and Sakari Sohlberg Foundation, the Finnish Cultural Foundation, and the Finnish Eye Foundation

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