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Specifically, HC induced a significant change in 15 proteins (i.e., 9 and 6 up- and down-regulated, respectively) involved in autophagy, including the down-regulation of NPC1 (Nieman-Pick type C) and QSOX1 (quiescin sulfhydryl oxidase 1) and the up-regulation of HMOX1 (heme oxygenase 1) and KDM4A (lysine demethylase 4A)

GHK-CU is a naturally occurring copper-binding peptide composed of three amino acids

GHK-Cu is the copper(II)-coordinated complex of the tripeptide glycyl-L-histidyl-L-lysine, abbreviated Gly-His-Lys or GHK

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Gently add the cleared lysate to the resin until the lysate has completely entered the column

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