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In innate immunity, Clostridium modulates macrophage polarization (shifting from pro-inflammatory M1 to anti-inflammatory M2), induces tolerogenic dendritic cell phenotypes to suppress excessive antigen presentation, regulates inflammatory body activity and neutrophil hyperactivation, and modulates ILC subsets to reinforce mucosal defense

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Cell 185 (5), 881895e20

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J Agric Food Chem 65(48):1038310394 Chen Y et al (2022) Mulberry leaf extract alleviates Staphylococcus aureus -induced conjunctivitis in rabbits via downregulation of NLRP3 inflammasome and upregulation of the Nrf2 system and suppression of pro-inflammatory cytokines