Injected to manage diabetes
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Furthermore, overexpressed circEPS15 could act as a miR-24-3p sponge, inhibit miR-24-3p expression in 1-methyl-4-phenyl pyridine (MPP + )-treated human neuroblastoma cells (SH-SY5Y cells), upregulate the expression of the target gene PINK1, decrease the protein level of SQSTM1/p62, upregulate LC3 expression, and enhance PINK1-Parkin-dependent mitophagy, which subsequently upregulated Bcl-2 and TOMM20 expression, and reduced BAX and Cleaved-Caspase-9 expression, preventing MPP + -induced neuronal damage
However, it's important to consult with a healthcare provider before starting any new supplement or medication
For patients with diabetes, monitoring for retinopathy is important, as rapid improvement in glycemic control with GLP-1 receptor agonists has been associated with temporary worsening of diabetic retinopathy in some cases
But its popular among philosophers