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Because the size of each protein domain is large compared to the surrounding solvent molecules, the solvent is coarse-grained out and its dynamics are not explicitly modeled
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For lyophilized vials, recommended freezer storage at 20 C or lower is cited
Dermatology 205:169171 Pascual JC, Matarredona J, Miralles J, Conesa V, Borras-Blasco J (2006) Oral and cutaneous lichenoid reaction secondary to imatinib: report of two cases
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