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Kidney disease as a risk factor for development of cardiovascular disease: a statement from the American Heart Association Councils on Kidney in Cardiovascular Disease, High Blood Pressure Research, Clinical Cardiology, and Epidemiology and Prevention

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ER decreases breast cancer cell survival by regulating the IRE1/XBP-1 pathway

While findings remain exploratory, the compound continues to be investigated for its potential biological roles

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Other mechanisms like mutations that enhance cytosolic levels or intensify intracellular signaling have also been associated with ASD (Krey and Dolmetsch, 2007)