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RNAi-based therapies hold significant promise for treating cancer, particularly due to their potential to target disease at the molecular level

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However, the absence of rigorous human safety data is a genuine limitation, not a clean bill of health no responsible source can claim these compounds are "completely safe." Several specific concerns deserve emphasis

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doi:10.1007/s13277-013-0778-z Li J, Long J, Hu Y, Tan A, Guo X, Zhang S (2012) Glutathione S-transferase M1, T1, and P1 polymorphisms and thyroid cancer risk: a meta-analysis