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These microbiome changes reversed rapidly, however, when the obese mice were returned to a normal, lean diet 79
This critical difference means it functions as a targeted lipolytic agent rather than a systemic hormone, allowing for fat metabolism enhancement without the appetite disruptions, cortisol elevation, or blood sugar effects associated with growth hormone therapy
Therefore, a man whose testosterone is pushed back up into the normal range by either SERMs, anastrazole, or HCG should have the same potential clinical benefit to sperm quality