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The irritation isn't coming from the peptide side of things

Many studies suggest that vitamin B12 is essential to developing the fetuss brain and nervous system

Blood 88(10):182a, 1996

The approximately 10-fold enhanced potency of IGF-1 DES compared to full-length IGF-1 means it produces maximal or near-maximal activation of these pathways at much lower concentrations, and because it is not sequestered by IGFBPs, a higher proportion of administered peptide reaches target tissues to drive these anabolic processes

Zinatizadeh MR, et al

A., Klett, E