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Result: Shedding peaked around month 5-6, then gradually decreased

The medication is establishing its presence, not yet operating at full therapeutic capacity

The reason for this is that the initial wave of drug-induced hepatocellular destruction is followed by a robust innate immune response, in which invading inflammatory cells release toxic oxidants and cause a second wave of destruction

I think [what the success of GLP-1s in helping people lose weight] underscores is how biology is really at play here, Kelly said

doi: 10.1186/s13063-023-07638-w