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Both products contain semaglutide as the sole active pharmaceutical ingredient, along with inactive ingredients like disodium hydrogen phosphate dihydrate, propylene glycol, phenol, and water for injection

GLP-1 RAs have been shown to induce phosphorylation and inactivation of NHE3 (Muskiet et al., 2017)

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In trial documents, its referred to as retatrutide or by its development code, LY3437943