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Some researchers also suggest glutathione can directly bind with the active site of tyrosinase (which contains copper), effectively inactivating the enzyme and further halting melanin synthesis

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However, when intracellular glutathione is well below this homeostatic level, GCL is no longer inhibited and can actively utilize the cysteine that NAC supplies

Characterization of the parasite TGR revealed enzymatic properties that differed from those of mammalian TGR, TrxR, and GR

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