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Targets 13 (2), 227234

[DOI] [PubMed] [Google Scholar] 25.Rosenstock J., Frias J., Jastreboff A.M., et al

Gradientdose 5-amino-1-methylquinolinium treatment further enables investigation of doseresponse relationships between NNMT inhibition, NAD+ levels, and metabolic efficiency, improving mechanistic understanding and supporting targetbased research for metabolic diseases

Discussion The results of this study show that ARA 290 (4 mg SC) self-administered for 28 d by subjects with type 2 diabetes is not associated with significant ARA 290-related adverse events