Jastreboff and colleagues studied the obesity Phase 2 in NEJM observing mean body weight reduction reaching approximately 24 percent at the 12 mg dose tier at 48 weeks (PMID 37366315)
Interestingly, GIP affects glucagon differently than GLP-1
Naturally, the surge in popularity of these weight loss drugs has prompted the supplement industry to jump on the GLP-1 bandwagon, with brands releasing so-called natural Ozempic and faux-zempic formulas
0.8%) in this 26-week, randomized, open-label study (70)
Published in the Lancet Psychiatry, the research also examined data on new diagnoses of anxiety and depression
It has been shown to influence cognitive function and reduce brain inflammation in pre-clinical models (Huber et al., 2024)