does tirzepatide increase insulin sensitivity 🧠Let's break the drug down using this mnemonic cloud!⁠ ⁠ 💉 Tirzepatide is a GLP-1 and GIP agonist. ⁠ ⁠ 🤔But what exactly is glucagon-like peptide (GLP-1) and gastric inhibitory polypeptide (GIP)? ⁠ ⁠ The catcher in the gut:

doi: 10.1038/sj.mp.4001507

Toxicology 241, 157166 (2007)

In order to qualify for the study patients had to be at least 18 years of age with a diagnosis of type 2 diabetes and treated for at least three months with diet and exercise and/or a stable regiment of metformin, as well as an HbA1c level of 7-10% and a body weight of 60-110 kg

Warnings and Precautions Tirzepatide carries an FDA black box warning regarding the potential risk of thyroid C-cell tumors, including medullary thyroid carcinoma (MTC), observed in rodent studies

Since the medication affects digestion, it can cause temporary discomfort as your body adjusts

J Cutan Pathol 42(5):308-17, 2015