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Authors suggested that the changes observed was due to the degradation and cleavage of glycoside bonds leading to macromolecule de-polymerization and oxidation of functional groups to maintain carboxyl, carbonyl compounds, hydroperoxides, lactones, and CO 2 (Pankaj et al

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NAD(+) Precursor Supplementation in Human Ageing: Clinical Evidence and Challenges. Nature Metabolism 7: 19741990