For people with genuine B12 deficiency or suboptimal levels, supplemental B12 can meaningfully improve energy levels, mental clarity, and exercise tolerance
Myostatin is a potential biomarker of sarcopenia [12], as it regulates transcription factors such as MEF2 and MyoD, consequently impairing myoblast proliferation and differentiation
The dermatological side effects include superficial oedema and skin rash (the most frequent side effects), pustular and/or lichenoid eruptions, erythroderma, graft-versus-host-like disease, and small-vessel vasculitis [8,9,10]
As years passed and additional variations hit the market, GLP-1s, like semaglutide (Ozempic), have garnered even more attention for their weight loss effects
And what the researchers did was compare patients taking GLP-1 medications to similar patients taking another type of diabetes drug called DPP-4 inhibitors, or gliptins
Front Pharmacol 12:670155