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Although the epidemiology and implications of the AF and DM comorbidity seem to be well described in the current literature [6, 7], the precise underlying pathogenic mechanisms still remain an issue of debate [8]

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The other 7 bullfrogs were injected into 1.5 mL centrifuge tubes with a 1 mL syringe, and then centrifuged at 4C for 10 min (12000 r/min, 4C) after 24 h

As the biological activity of yohimbine, especially the regulation of metabolism related to obesity and its role in the treatment of erectile dysfunction, is similar to the well-documented properties of H 2 S, it seems that the mechanism of yohimbine action can be at least partially associated with the regulatory properties of reactive sulfur species, including H 2 S and sulfane sulfur