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Biliary complications (cholelithiasis, cholecystitis) represent a class effect attributable to reduced gallbladder motility, with incidence approximately 1.5-2.5-fold higher than placebo in long-term trials

The Problem Most people struggling with weight arent failing because of willpower

Patients with obesity may be appropriately treated with diabetes-approved GLP-1 RAs if they also have a diagnosis of T2DM, though claims data may not fully capture this information

Per a 2024 KFF Health Tracking poll, around 12% of U.S

If patients receive GLP1 medications outside their primary health system (for example, from telehealth) or change providers during the treatment, the EHR data collected in our study may not capture the full course of treatment, and this may explain our observation of generally shorter treatment durations, and hence less weight loss, recorded in EHRs

Mice in the sham group were injected with an equivalent volume of saline, 6 % propylene glycol, and 6 % alcohol