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The Journal of Biological Chemistry

However, STEP 1 extension concluded that 1-year withdrawal of semaglutide results in regain of two-thirds of prior weight loss [97], highlighting that withdrawal of semaglutide results in weight regain which may be problematic in older adults who are already using polypharmacy approaches for comorbid disease

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For replating, HBs were dissociated using Accutase and reseeded onto Matrigel-coated plates