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Because Accutane delays wound healing, cosmetic procedures such as dermabrasion, skin resurfacing or exfoliation, plastic surgery, chemical peels, laser treatments for acne scars or tattoo removal, laser hair removal, and waxing should be avoided

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Snchez-Aranguren LC, Prada CE, Riao-Medina CE, et al

It also counteracts the increased appetite that follows weight loss [112, 113]

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Further experiments indicated that suppressing the expression of VGF in the TC1-6 cell line led to the accumulation of glucagon near the Golgi apparatus, as well as reduced glucagon secretion and decreased glucagon peptide maturation (Fig