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GLP attenuates HSC activation, collagen deposition, and -SMA expression by suppressing TGF-/Smad and TLR4/NF-B signaling, modulating ECMreceptor interactions via downregulation of integrins (e.g., ITGA6, ITGA8), and influencing apoptosis and cell cycle regulators

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The delta sleep-inducing peptide inhibits CRH at the hypothalamic level, reducing the signal that drives ACTH release and, downstream, cortisol secretion from the adrenal glands

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En hemodilisis, administrar en la va de retorno en los 10 ltimos minutos del procedimiento

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Fonte:PubMed

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