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They may be helpful in nonalcoholic fatty liver disease (NAFLD), which is also a risk factor for heart disease [27], [33]

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Thus, incretin receptor agonist-induced weight loss would be expected to create a tissue environment that is less conducive to fibrosis [34]

however, the underlying mechanisms are uncertain, due to the fact that some TH actions on glucose tolerance and insulin sensitivity in different tissues may have divergent influences on blood glucose levels 35