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Even moderate doses (8 mg) led to ~2223% weight loss, highlighting a dose-responsive effect
While there is potential mechanistic overlap with DPP-4 inhibitors or dual GLP/GIP receptor agonists we focus the current review on GLP-1RAs due to preponderance and availability of longer-term data, as well as the significantly higher market penetrance of this drug class
12 These effects could be secondary to reduced hepatic lipogenesis, increased fatty acid oxidation and modulation of lipoprotein metabolism
However, if one needs reductions in both fasting and postprandial glucose levels a longer acting agent such as repaglinide is a better choice
The dosing is completely different between the two medications and it does not translate between them
But as more research came out about the non-weight-loss benefits of GLP-1s and the reduced risk for multiple chronic diseases (due to the inflammatory pathways that the medication addresses), Dr
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