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in Mucosal Immunology 3rd edn (eds Mestecky, J

GHK-Cu (copper peptide) GHK-Cu is a naturally occurring tripeptide that binds copper and plays a central role in tissue remodeling, wound healing, and hair follicle regulation

The KTTKS sequence is derived from the C-terminal propeptide of type I procollagen and acts as a matrikine -- a peptide fragment that signals cells to produce new extracellular matrix components

This is why it has been used in skincare products for ages

Effect sizes differences were medium to large

The latter degrades excess toxic haem with release of ferritin, bilirubin (via biliverdin) and carbon monoxide