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This decrease was irrespective of cirrhosis etiology and thought to reflect diminished hepatic GSH synthesis

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Factors driving the inter-individual variability in the metabolism and bioavailability of (poly)phenolic metabolites: A systematic review of human studies

Genetic variation in glutathione synthesis genes (GCLC, GCLM) and detoxification pathways (GST polymorphisms) influences baseline glutathione levels and responsiveness to supplementation

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