However, the retina deserves attention too because rapid improvement in glucose control has long been known to occasionally cause temporary worsening of diabetic retinopathy
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It takes another 7 years (approximately) for such cells to develop subclones with metastatic capacity and another 3 years (approximately) before the disease will be diagnosed due to clinical symptoms and a clinically apparent primary tumor accompanied by metastases (13)
[DOI] [PMC free article] [PubMed] [Google Scholar] 33.Simon G.E., et al