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Retatrutide's T2DM Phase 2 trial demonstrated HbA1c reductions of 1.3% to 2.0% across dose levels, with 82% of participants reaching an HbA1c of 6.5%

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Rybelsus uses an oral absorption enhancer (SNAC) for gastrointestinal uptake, while Ozempic is a weekly subcutaneous injection

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