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Another Phase I/II trial (NCT04078308) involving newly diagnosed TD1M patients revealed that MSC infusion improved HbA1c levels, increased C-peptide levels, and shifted cytokine profiles from pro-inflammatory to anti-inflammatory

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To assess the clinical relevance of this relationship, we utilized publicly-available datasets (GSE32269 and DbGaP) to determine the correlation between GLP1R and a negative Notch signaling mRNA signature in prostate cancer patients (Figure 5E-F)