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The Good News: Why Semaglutide Usually Lowers Blood Pressure Patients taking semaglutide usually lose weight and improve their blood sugar regulation, which frequently goes hand in hand with lowered blood pressure

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The SURMOUNT-1 trial enrolled 2,539 adults with obesity or overweight and demonstrated weight loss of 15 percent at the 5 mg dose, 19.5 percent at the 10 mg dose, and 20.9 percent at the 15 mg dose over 72 weeks

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GLP-1s are intended to function as an addition to lifestyle intervention, not a standalone solution, and are most effective when used as part of a comprehensive approach that includes dietary modification, physical activity, and behavioral support