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IGF-1 plays a central role in tissue repair and cell growth but should be used cautiously due to its proliferative effects. Pollak, Nature Reviews Cancer Stacking HGH and IGF-1 increases potential benefitsbut also compounds side effect risks if not carefully managed

To minimize TMAO production, it is vital to adhere to the divided dosing strategy, keeping single doses under 1,000 mg to ensure maximum small intestinal absorption and minimal spillover into the large intestine