Long-term follow-up studies are needed to assess durability of therapeutic effects and to identify any delayed adverse effects or complications that might not be apparent in shorter-term investigations
B12 levels can be affected by nutrition, genetics, and the gut microbiome
Localization of the motor hand area to a knob on the precentral gyrus
1 2 "How I Treat: How I treat cobalamin (vitamin B12) deficiency"
Curcumin appears to modulate novel gutliver endocrine axes by suppressing GIP release from hypoxic intestinal tissue, thereby attenuating adipose inflammation, and by coordinating hepatocyte cell death pathwayspromoting autophagy (BECN1, p62) while inhibiting pyroptosis (Gasdermin D, caspase-1, TNF-, IL-1)
Storage & Handling Store refrigerated (28 C), dry and protected from light