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Beyond cellular assays, the study also explored the structural properties and histone-binding potential of the Epitalon peptide through computational modeling and molecular docking simulations

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In this study, embryonic stem cells were transfected with a dominant-negative N-cadherin mutant (NCAD delta) under the control of the Villin promoter, which is active primarily in intestinal epithelial cells, and then were introduced into C57BL/6 mouse blastocysts

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