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500 The study revealed that patients receiving a single intravenous dose of ustekinumab (130 mg or 6 mg/kg) followed by a maintenance dose of 90 mg subcutaneously every 8 weeks experienced a significant reduction in symptoms such as rectal bleeding and no significant adverse events

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As we age, NAD+ levels in our skin naturally decline, contributing to the visible signs of aging such as thinning, wrinkling, and uneven skin tone

Advertising campaigns emphasized the benefits while downplaying or omitting information about serious gastrointestinal risks that emerged in clinical data and post-market surveillance