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According to the American Cancer Society (ACS), it can have a Chemotherapy injections may cause typical injection site reaction symptoms, including: skin discoloration swelling itching tenderness warmth However, chemotherapy drugs sometimes cause a symptom known as extravasation, which is when the medication leaks from the vein and into the surrounding tissue

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Schmidt L, Duh F-M, Chen F, Kishida T, Glenn G, Choyke P, et al

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