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Post-meal glucose spikes, the spikes that drive cravings and stall weight loss, remain entirely invisible to most patients

Health insurers will be well served to begin quantifying GLP-1s cost impact on the portfolio for the short and long term, which will vary by market and product, to determine any necessary premium adjustments or changes to underwriting philosophy

Any consideration of GLP-1 therapy should involve comprehensive evaluation by an endocrinologist or appropriate specialist, with clear discussion of the investigational nature of this approach, potential risks, costs, and the importance of ongoing monitoring

Most of the ATP in a cell is generated by the combined action of the TCA cycle and oxidative phosphorylation (OXPHOS) within the mitochondria 73,74

January 2011;57(1):122127

Evaluate published statistics with appropriate context