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During host cell infection, CoVs trigger an imbalance involving increased ROS production and reduced antioxidant host responses, thereby leading to increased redox stress, reduced antiviral host responses, and increased virus-induced inflammation and apoptosis, ultimately causing cell and tissue damage and end-organ disease 3

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By the time a chronic disease shows up on a lab test, it has often been developing quietly for a decade or more

Melanoma metastases are highly dependent on the SSP in nutrient-limited environments, and PHGDH knockout or inhibition markedly suppresses the metastatic capacity of melanoma in mouse models (88)

6b, c and Supplementary Fig