While the therapy still showed a favourable safety profile and Novo plans further higher-dose trials, todays outcome underscores how small differences in efficacy can have outsized implications for commercial positioning and investor sentiment in weight-loss drug development
8 mg per week Resulted in substantial body weight decreases, suggesting it may offer an optimal balance between efficacy and tolerability
Triple-Hormone-Receptor Agonist Retatrutide for Obesity - A Phase 2 Trial (PubMed record)
95% CI 0.410.95)
Quarenghi, M., Capelli, S., Galligani, G., Giana, A., Preatoni, G., & Turri Quarenghi, R
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