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Antiretroviral treatment leading to secondary trimethylaminuria: Genetic associations and successful management with riboflavin

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Glutathione, which exists in oxidized and reduced form, is involved in maintaining the redox potential of the cell cytoplasm

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Together, these observations suggest that receptor-level signaling and anti-inflammatory effects alone may be insufficient to produce functional improvement in energy-demanding tissues such as skeletal muscle and brain, where substrate turnover and mitochondrial metabolic throughput are critical determinants of tissue function